Biology 2581B Lecture Notes - Lecture 12: Haplotype, Chromosome, Immunoprecipitation
18 Mar 2020
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Document Summary
Nts ( snps) which show variation between individuals through mutation and. 1h inherited like any allelic variant otherwise just variation. Haplotype : a series of adjacent common human genetic variants. Snps , less tend to tends to get recombination inherited together ( on same chromosome) get inherited together (2 possibilities) (2 possibilities) (2 possibilities) Use tag snps to identify a haplotype only few tag snps needed since many inherited together. Atc these snps are found in these locations almost certainly contain same. Rare recombination ( c 50% ) between locus 2 and rpg linked. Gene dosage and breakpoints may affect phenotype. Improper repair after ds homologous breaks recombination ( nahr) 799. 9% variants genome differs as chromosome non - allelic homologous a template sections used from reference at. 2100 - 2500 variants variants consist (fewer) of. Snps and short lndel affect more gps in a genome - 20 mbp. Shared across all continents > shared across continents > private to continent.
