Biology 2581B Lecture Notes - Lecture 17: Kinetoplast, Cytosine, Chloroplast
10 May 2016
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Amount / relative ratio to non-coding dnas. Packaging system: how are exons organized / separated in relations to the non-coding dnas (scrambled vs ordered) Contents of non-coding dna: regulatory element, repeats mobile elements, pseudogenes (remnants of dnas that used to be useful), foreign dna, arrangement of exons. Overview: there"s a huge diversity in genome architecture between different organisms, differences in genome architecture. Genome size in different organisms & in different organelles (nuc vs mito vs chloro) Genome compositions/contents: standard vs nonstandard coding system, atgc composition, relative ratios of nucleotide bases, amount of cpg sites / other methylation sites, coding dnas, non-coding dnas. Types of mutation review previous notes, all can cause different phenotypes: look over point mutations, chromosomal mutations, addition of foreign dna through mobile elements. Also, remember that red bull can cause genome fragmentation: genomic mutations. Chromosomal insertion, duplications, rearrangements, fragmentations (often), fusions, chromosomal deletion (rare) Recombination can be seen as a mutational event, a rearrangement of genome structure.
