Biology 3338A Lecture Notes - Lecture 23: Follistatin, Rna, Neural Pathway

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* the mesoderm starts as a ring of tissue that flips itself inside out through involution, then you have convergent extension driving the dorsal side. * you end up with a ball of mesoderm, inside that ball of mesoderm you have endoderm and outside you have ecto. * that ball of mesoderm (if you look at a cross section of an embryo) has different properties to it. * dorsal mesoderm (on the dorsal midline, is the one that went through the dorsal organizer) is going to form notochord. * as you get further away from dorsal you get different types of mesoderm. * dorsal organizer has to do with localization with maternal determinants. So in the end you end up with b catenin localized opposite to sep while other maternal determinants localized at the vegital half. And together this overlap forms the nieuwkoop center and dorsal organizer. * the dorsal organizer (cells of do move) while nieuwkoop center don"t move.

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