Biology 3592A Lecture Notes - Lecture 9: Transfer Rna, Genetic Load, Mitochondrial Disease
7 Oct 2016
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Contains its own dna but needs dna from nucleus to express some genes. Double membrane structure came from endosymbiotic event. Mitochondria was a bacterium that had a symbiotic relationship. Mitochondrial genome has 37 genes and lost many genes from when it was bacteria. Ribosomes inside mitochondria as well not all the genes necessary for transcription and translation of mitochondrial genes. Denaturing 2 strands of dna found one strand is heavier. Oh and ol are origins of replication not only does this stuff need to be produced, it needs to be replicated too. Promoter number 2 transcribes basically whole chromosome. Within any given mitochondria you will have many copies of mito dna, then you"ll have many mitos in a cell. Cells that require more mitochondria (cns and muscle) are gonna be more affected by mitochondrial diseases. Active process to break down paternal mitochondria. Not only might mitochondrial dna during replication be random, but the segregation forming.
