Biology 1001A Lecture Notes - Lecture 13: Gene Flow, Mutation, Assortative Mating

• School: Western University
• Department: Biology
• Course: Biology 1001A
• Professor: Tom Haffie

Document Summary

Selection, drift, and other disruptions of hardy-weinberg equilibrium. Evolution (cid:862)a (cid:272)ha(cid:374)ge i(cid:374) allele f(cid:396)e(cid:395)ue(cid:374)(cid:272)ies(cid:863) if there is a change in allele frequencies, the population is evolving. Absolute and relative fitness (cid:862)a(cid:448)e(cid:396)age (cid:374)u(cid:373)(cid:271)e(cid:396) of su(cid:396)(cid:448)i(cid:448)i(cid:374)g offsp(cid:396)i(cid:374)g fo(cid:396) ea(cid:272)h ge(cid:374)ot(cid:455)pe is defi(cid:374)ed as its absolute fitness(cid:863) Selection (cid:862) ele(cid:272)tio(cid:374) o(cid:272)(cid:272)u(cid:396)s (cid:449)he(cid:374) (cid:374)ot all ge(cid:374)ot(cid:455)pes a(cid:396)e e(cid:395)uall(cid:455) fit. (cid:863) Divide by absolute fitness of most successful genotype to calculate relative fitness, denoted w. Most successful genotype (wmax) has a w-value/relative fitness of 1. All others would be a fraction of 1, w = w/wmax. If waa =20, waa =15 and waa = 12, what is waa (the relative fitness of genotype aa?) Which of these situations describes heterozygote advantage? (genotypes: waa = waa = waa, waa = Waa < waa, waa < waa > waa, waa > waa > waa) The heterozygotes are greater in number than either homozygote of the same species. Eliminates genetic variation, as the rare allele is selected against.