Biology 1001A Lecture 8: Origin of Variation Outcomes.docx
Document Summary
Cutting and pasting four dna backbones results in one recombination event stage of meiosis when recombination occurs: recombination is first source of genetic variability produced by meiosis, chromatids generate new combinations of alleles by physical exchange of segments, exchange process involves precise breakage, and joining of dna, catalyzed by enzymes, occurs when chromosomes help tightly together by synaptonemal complex, crossover visible at late prophase 1; reflects exchanged genetic material. 1. 2 million variants in human genome sequence: of variant bases are single nucleotide polymorphism, copy number variation, inversions etc (each person has 1000 cnv affecting 35% of genes) each person has about 300 variants in insertion of retro elements (lines, sines) mobile element structure of is elements, transposons, retrotransposons and retroviruses (see is outcomes) types of evidence that would be useful in determining how long the human genome has been infected by a given mobile element.
