Biology 1002B Lecture Notes - Lecture 17: Tumor Suppressor Gene, Spindle Apparatus, Protein Kinase
19 Mar 2016
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Some may degrade at specific stages whereas others might be synthesized: cyclin-dependent kinases (cdks) a type of protein kinase that phosphorylates, and thereby regulates protein activity. S and to commit the cell to dna replication: g2/m checkpoint, between g2 and m phases. Anuj gupta: the complex that forms is required for the transition from g2 to m and the progression of the cell through mitosis, checkpoints are like brakes, and could be inactivated by a mutation or chemical modification. Regulation of the mitotic cell cycle by internal controls. Complexes of cyclins and cyclin-dependent kinases (cdks) regulate the progression of the cell through the cell cycle. The three cyclin cdks present in all eukaryotes are shown. The cdks are present throughout the cell cycle, but they are active only when complexed with a cyclin (shown by the broad arrows in the figure).
