Biology 1202B Lecture Notes - Lecture 23: Rna World, Ribozyme, Base Pair

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Biology1202b rna word and rna patrick mcdonald - monday, march 21, 2016. Acts both to store informaion and provide catalyic (enzymaic) acivity. Life requires the ability to catalyze reacions that lead directly or indirectly to the producion of more molecules like themselves. Rna has the unique potenial to act as both an informaion carrier and catalyst (providing also the ability of self-replicaion) Assembly of rna polymers in the rna world is random. Funcion will depend on sequence (which is dependent on structure) Given any amount of ime, any possible event will typically come true. Clicker (test) quesion: which property of rna allows some rna molecules to act as catalysts? (think ribozymes) They are single-stranded molecules which can fold into very speciic shapes. Remember, like proteins, rna structure determine catalyic/enzymaic acivity. Generate a large pool of random dna molecules (simulaing the events in the clay of primordial earth) Simulates the random transcripion of primordial rna molecules.

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