Biology 3444F/G Lecture Notes - Lecture 2: Molecular Marker, Genetic Marker, Nuclear Dna
17 Apr 2014
School
Department
Course
Professor
Document Summary
Marker: entity used as indicator of some other entity or process. Tells us about something else we"re interested in (indirect). Different markers have different characteristics often trade offs when choosing which marker. Molecular marker: molecule that tells us something about an individual. Propensity to develop particular disease. Probability of particular phenotype. Genetic marker: a distinct, heritable indicator of identity and ancestry. At the highest level of ancestry, know what species they belong to. Can tell where they come from and who they are. Markers in humans: mtdna locus & y- chromosome microsatellites and snps. Environment affecting phenotypic plasticity means a good marker must be heritable, not influenced by the environment and variable. Ultimately work at dna level for molecular (genetic) markers. In animal cell find dna in the nucleus and mitochondria. Plant cells also have dna in the chloroplast. Conservation of structure of genome and sequence in certain areas is really handy for tracing lineage.
