Biology 3602A/B Lecture Notes - Lecture 30: Myocyte, Lipid Droplet, Vo2 Max

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Review: proportion of diff types of muscle fibres differs among species, within individuals, and within muscles fibres in individuals. E. g. sprinter and marathon runner have very diff macromuscles which carries down to the micro level as well. Or having the physiological machinery that allows you to run far and fast. How they did it: measured both behaviour and physiology, and then they selected animals that liked to run and bred them together. Measured behaviour, and measured the physiological ability to run using the vo2max. Mice were not trained to run on wheel; some liked to run, and some didn"t. High runners were bred together and measured wheel running in offspring. Other control group were of 2 randomly bred mice. Continued this for many generations; for each generation, they took animals that have never seen a wheel before, exposed it to them, and measured their tendency to run, and measured the vo2max.

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