Biology 3660A/B Lecture 26: 3601 Lec 26
Document Summary
High km = low affinity large vmax: trade offs occurs (cid:224) binding tightly, not as fast reaction, high km = always reactions, but rate is slowed down, km = vmax, 1/enzyme substrate binding affinity, kcat = rate of substrate processing by the enzyme, eg. Performance declines either side of optimum temperature: acute response (cid:224) thermal performance curve, curve is asymmetric exponential increase until it peaks to optimum , decline as temperature increase is very steep, pejus range worse range, decline of rate of performance range, degradation of proteins occur at high range, protein degradation not necessarily the main cause of death. Reaction norms: longer term responses to temperature, reaction norms are usually developmental, looking at genotype vs the environment, effectively, looking at gxe interactions, development time and survival graphs, no difference between cool and warm environments in hot/cold place, washington shows decrease in survival (cid:224) can"t acclimate to hot.