Health Sciences 3701A/B Lecture Notes - Lecture 7: Coronary Artery Disease, Angina Pectoris, Coronary Circulation

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Increase in fatty tissue in outermost layer of heart. Contractile strength decreased as well as stroke volume, cardiac output and ejection fration and heart rate. Thickening and sclerosis (hardening) of the valve flaps. Some loss in muscle cells in av and bundle of his. Decline in cardiac output - less oxygen to blood. Increase in arterial fibrillation (irregular, rapid heartbeat) and incidence of heart block. Blood components volume of blood decreases hemoglobin and hematocrit levels diminished. Both lead to ischemic heart disease (decrease in blood supply to heart) and cerebral ischemia (lack of blood supply to brain) Their progress involves building up and breaking down of plaques. Ldl influencing building up of fatty streaks on wall. Hdl transport excess lipid from the peripheral tissues to liver: statin cholesterol reducing medication. Hypertension: systolic greater than 140 and diastolic greater than 90.

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