Kinesiology 2230A/B Lecture Notes - Lecture 9: Vo2 Max, Carbamino, Reversible Reaction

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Lecture 4 ph and h+ acid base balance. Ph scale is logarithmic: o(cid:374)e u(cid:374)it (cid:272)ha(cid:374)ge i(cid:374) ph = (cid:1005)(cid:1004)(cid:454)(cid:859)s (cid:272)ha(cid:374)ge i(cid:374) h, looking at h+ concentration. Stomach acid (hcl) ph 1. 0; blood 7. 1. Co2 + h20 h2co2 (h+) + hco3. Relatively small ph change in the blood. Muscle: lower ph at rest/normal conditions, drops to ph further (6. 6) than blood (6. 9, based on [h+] in fluid in cell. See greater change in ph in muscle compared to blood due to dilution effect of h+ entering blood plasma after dissociating from lactate. Ppo(cid:1006) at lu(cid:374)gs di(cid:272)tated (cid:271)(cid:455) : atmospheric conditions/barometric pressure, sea level 159mmhg. Doing exercise, o2 delivered by blood o2 dissolved in blood plasma: dissolved o2 dictates partial pressure of oxygen. Ppo2 at muscle: aerobic exercise, using o2 from blood delivered via hb, o2 dissolved in blood plasma, dictates ppo2, not hb that dictates ppo2, ppo2 at muscle decreases, affinity of hb to o2 decreases.

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