Kinesiology 2230A/B Lecture Notes - Lecture 3: Acetyl-Coa, Citric Acid Cycle, Isocitric Acid
30 Oct 2017
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Track & rowing & soccer: 10% anaerobic, 80% time in low intensity = aerobic, avg. Cofactors & coenzymes: cofactor: a non protein component of enzymes, a lot are metals, coenzyme: organic, come from vitamins. Acetyl coa: make a part of the active site, without this the enzyme wont function, niacin = nad, activity of some enzymes are under complex control, feedback inhibition. Substances at the end of a series of reactions inhibits reaction at the beginning: affinity of the enzyme or substrate will affect the rate of an enzyme catalyzed reaction, ex. Feedback inhibition & acceleration = atp & adp- stopping things earlier in the pathway. Feed forward control = enabling changes later in the pathway: rate-limiting, marker or regulatory enzymes, the enzyme in the metabolic pathway where the slowest reaction is exerted. In krebs cycle = cs (citrate synthase) & isocitrate dehydrogenase - aerobic.
