Kinesiology 4430F/G Lecture 12: 12 Bone
20 Dec 2017
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Document Summary
Osteoporosis clinical condition where you lose bone to a certain degree. #1 risk factor for fracture in post-menopausal women. Can be changed/prolonged with pa and lifestyle choices. Healthy bone thick cortical layer and trabecular bone instead. Bone loss- thinning of cortical bone and loss/thinner of intra-trabecular network that adds strength to the bone: makes bone more susceptible to fracture. If you use bone up (osteoporosis) absorb it from endosteum. Osteoclasts: hematopoietic origin same origin as blood cells and similar function, phagocytic activity, produced in bone marrow, precursor cells in blood fuse to form osteoclasts absorb damaged/old bone. Osteoblasts: mesenchymal origin derive from same tissue as collagen, produced in bone marrow, synthesize bone matrix. Osteocytes: mature osteoblasts (black dots) are trapped in the bone matrix that they have laid down, control mineral exchange, signal loading of the bone/stresses placed on them.
