Microbiology and Immunology 2500A/B Lecture Notes - Lecture 19: Influenza Vaccine, Measles Virus, Cytopathic Effect
29 Sep 2017
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Document Summary
Only when the virus has completely budded and ready to infect next cell: therefor infectivity is only when before entering cell and when a virion upon exit. Overview of the viral infectious cycle: the example of ebola virus infectious replication. Host is constantly trying to fight steps to. None of these steps can occur without the host. We try and destroy different parts of the cycle in vaccines. Viral infectious cycle requires the host cell machinery: Bacteria replicate by binary fission, the splitting of a single cell into two cells. Maturation = assembly of genome and viral proteins. Viruses makes their bits and pieces (using the host) and then assemble an infectious virion. For a long period of time: not harmful when it first enters, just losing shell and making what it wants to make, can take 8 to 48 hours which is much slower than bacteria.
