Microbiology and Immunology 3300B Lecture Notes - Lecture 1: Innate Immune System, Antigen, Epitope
9 Dec 2016
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Document Summary
Cellular responses effective at killing our cells. Pore-forming proteins (blow hole in membranes of cells they encounter) Immune system can be a dangerous things can produce bad things: Reactive chemicals bleach (hclo), hydrogen peroxide (h2o2) Antibodies target any cell for destruction. Immune system is very potent because we live in a dangerous world bacterial. Pathogens fall into two areas of body extracellular and intracellular pathogens, viruses, fungal pathogens, single cell eukaryotic organisms, and small animals (helminthes: interstitial (space between cells), blood, lymph bacteria, protozoa, Extracellular found in one of two places: fungi, worms, viruses: epithelial surfaces (lining of tracts) same as above. All classes of pathogens can be found in extracellular. Intracellular pathogens: cytoplasmic viruses, bacteria, protozoa, vesicular (pathogen enters cell through endocytosis, inside a membrane bound compartment inside the cell but not released into cytoplasm) bacteria, fungi, viruses through the circulation to other places causing inflammatory response.
