Microbiology and Immunology 3820A Lecture Notes - Lecture 9: Pelvic Pain, Pelvic Inflammatory Disease, Gonorrhea
26 Nov 2017
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Neisseria gonorrhoeae: gram negeative diplococci, usually intracellular, fastidious: needs special enriched media and co2. Neisseria gonorrhoeae: infection syndromes: urethritis/cervicitis (occasionally pharyngitis and proctitis, arthritis-dermatitis syndrome, monoarthritis (classically, prepubescent females: vaginitis. Incidence dropped dramatically in developed countries: le clapatier paris neigh(cid:271)orhood (cid:272)lapoire, margret (cid:862)mother(cid:863) (cid:272)lap, profuse, inflammatory urethral discharge in males, female often asymptomatic, but at risk for pid, dgi. Complications of gonorrhoea: disseminated infections: sepsis, skin, joints, fitz-hugh-curtis syndrome (perihepatitis, ophthalmia neonatrorum, pelvic inflammatory disease (chronic pelvic pain and sterility) Diagnosis of gonorrhoea: urethral, cervical (not vaginal), throat, rectal swabs as appropriate, tropical gram stain of genital specimens: presumptive diagnosis in males, not females. Inoculation of selective medium (e. g. thayer-martin) at bedside: gene probe commercially available but give no info on antibiotic resistance. Id of this organism often results in civil or criminal proceedings. Isolation from prepubescent females in prima facie evidence of sexual abuse: lab will confirm identity at least 2 independent ways.
