Pathology 3240A Lecture 2: Class 2.docx
3 Mar 2014
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Case: runner, died of heart attack at 53, father died at 43 of the same thing, bad life style before, genetic or environment, probably both, lived longer than father, had better lifestyle. Down"s syndrome: facial changes, congenital heart defects, simian crease (on hand one crease, mental delay, umbilical hernia, predisposition to leukemia. Other classification injury inflammation infection immunological: immune system can: over react/excessive (ie. mosquito bite, anaphylaxis) act against itself, mount response against the body"s own cells, ex. Rheumatoid arthritis younger people immune system starts to recognize antigens in joint as foreign and attacks it releases mediators, breaks it down, damages joint can cause chronic damage to joint decreased or absent ex. Primary (scids, hiv) or treatment related (chemotherapy) neoplasia: new growth , autonomous proliferation of cells, usually creates a mass or tumour tumour is just a mass (ie. mole) can be benign if becomes malignant (can change colour) and become melanoma.
