Pathology 3240A Lecture Notes - Lecture 1: Experimental Pathology, Immunohistochemistry, Gross Examination
25 May 2016
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Document Summary
The study of the structural and functional changes in cells, tissue, and organs that underlie disease. Use a variety of techniques to diagnose, understand, and define disease. Pathology the bridge between the basic sciences and the applied sciences. Clinical support: guidance in treatment (e. g. staging of cancer) Autopsy: determination of cause of death; forensic autopsies (medical and legal factors) Research: experimental pathology; mechanisms, complications, and sequelae of disease; models of disease (animal or human tissue) Cytologic preparation: looking at individual cells rather than removing a chunk of tissue. The definition and causes of disease i. Disease the pattern of response of living organisms to injury. We identify disease by the appearance of physical signs. These however, are late findings, after action at the cellular level. Injury as a result of environment or genetic insult. When cells fail to adapt to the injury, or the adaptive mechanism itself becomes harmful, disease results.
