Pathology 3245B Lecture Notes - Lecture 3: Benign Prostatic Hyperplasia, Prostate Cancer, Urinary Retention
3 Feb 2017
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Document Summary
Genital tract prostate gland armstrong. Prostate surrounds the urethra & can often restrict urinary flow. Cross-section (slide 3) shows the urethra in the middle. May help close off bladder/urethra neck during sex (prevents retrograde ejaculation) Has contractile proteins to help close off urethra. Glandular differentiated carcinoma is common adenocarcinoma. Basal layer ix examined to determined if the tumour is malignant: well differentiation = no invasion yet, can be used to tell if invasion has occurred, or if it is still benign. Benign prostatic hyperplasia tends to be the central aspect. Very common effects most men after age 40. 2-5x normal weight (walnut size to tangerine) Decreased force of urinary stream: chronic obstruction complications. Bladder hypertrophy, dilation bladder needs to work harder. Urinary flow abnormalities cause urinary stone formation. Bladder traveculation (dilatation) & hypertrophy + stone in the bladder. Anti-androgens minimizes hyperplastic drive: surgery to open up urethra channel. 1 in 7 chance of being diagnosed during lifetime.
