Pathology 3245B Lecture Notes - Lecture 2: Restrictive Lung Disease, Cancer Staging, Pleurisy
16 Jan 2018
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Disease of the lung dr. kwan: affect 3 million canadians, . 8 billion spent to treat per year, increased cases in women. All lined by specialized, delicate lining (1-2 cells thick) this is: alveolar wall/alveolar septae site of gas transfer where gas exchange occurs, wall only 3 cells thick. Lung failure: lungs can be injured by: air (exposed to 10,000l of air/day) or blood. Injury to the muco-ciliary apparatus (cigarette smoke, burn victims inhaling hot or corrosive gases, viral diseases) Interference with alveolar macrophages (alcohol, malnutrition: accumulation of fluid or secretions in alveoli (pulmonary edema, cystic fibrosis) Include: gram negative bacilli(e. coli, etc. , pseudomonas aeruginosa, staph aureus, oral anaerobes. Inflammation of the lung secondary to infection: aspiration, inhalation, blood, direct inoculation, factors which determine if infection will occur, classification of pneumonia (most important classification clinical) Cigarettes: 30 yr old, smokes 15cigs/day = life expectancy shortened by >5 years, associated with, lung disease, cardiov.
