Pathology 2420A Lecture Notes - Lecture 3: Granulation Tissue, Blood Vessel, Transudate
9 Dec 2016
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Document Summary
Responsible for mediating vascular and cellular responses in inflammation. chemotaxis - phenomenon that guides and attracts wbcs to the site of injury. When a tissue is injured, an inflammatory reaction occurs at the site. The purpose of these reactions is to: destroy or limit spead of injurious agent, allow for repair or replacement of damaged tissue. Inflammation is dynamic and ever-changing and consist of a chain of reaction that overlap. The injury must be non-lethal tissue cannot be destroyed. The inflammatory reaction is non-specific intensity, duration, and outcome are modifiable factors. Bacteria, fungi or viruses that cause damage by release of toxins onto host cell: trauma. Includes penetrating, thermal or chemical injury and blunt trauma: immunologically-mediated, as a result of lass of blood supply. Frequently a transient vasoconstriction of arterioles mediated by nerves to smooth muscle within the arteriolar walls following injury brief process (5 mins)
