Pathology 3500 Lecture Notes - Lecture 3: Cirrhosis, Trypsin, Lipoprotein

• School: Western University
• Department: Pathology
• Course: Pathology 3500
• Professor: shepherd

Document Summary

Lecture 3- cell injury, adaptation and death ii. Key cellular targets: cell membranes, mito, nucleus- dna, cytoskeletal proteins, once a cell stops working properly everything starts shutting down. If we did we could find a way to reverse and go back to reversible injury. Cell injury: response to injury depends on type, duration and severity, consequences on cell injury depend on type, state and adaptability of injured cell, all injury is not universal. If effecting mito, the cannot produce atp which gives the cell even less energy: this can only happen for so long until cell bursts at some point this will become irreversible. Hydropic swelling in renal tubules: blood supply comes in the artery in the kidney, they start to swell and are pale because of the water entering. If (cid:455)ou do(cid:374)"t get e(cid:374)ough (cid:271)lood the kid(cid:374)e(cid:455) tu(cid:271)ules (cid:272)a(cid:374)t (cid:449)ork (cid:448)er(cid:455) (cid:449)ell. Point where reversible becomes irreversible is a bit foggy.