Pathology 3500 Lecture 26: Lecture 26
28 Mar 2018
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Document Summary
Pretty much is everything is in the lecture notes. Perinatal infections: hydropic fetus: baby swollen with water, end stage of many diseases in utero. So if the women handles the cat litter or they ocysts can spread in the air. She transmits this to fetus - it causes miscarriage and stillbirth and eye problems and neurologic problems. 2 routes of infection: transcervical - coming up from cervix into uterus cavity - ascending, transplacental - "hematological" - comes from blood stream going to placenta going to baby, toxoplasma uses transplacental. Transplacental infections - viruses, parasites, bacteria: torch, toxoplasma, rubella, cmv, herpes (this is transcervical also, torch organisms can cause inflammation of brain, eye, myocardial muscle of heart, can cause anemia , phenomia, all in fetus. If aquired early (1st trimester) infections may increase: growth retardation. Intellectual disability: cataract s, congenital cardiac abnormalities. In baby these infections can cause pneumonia, meningitis and sepsis.
