Pharmacology 2060A/B Lecture Notes - Lecture 17: Fecal Occult Blood, Bone Marrow Suppression, Multiple Drug Resistance

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17. 1 cancer referred to as neoplastic, meaning they have abnormal and uncontrollable cell growth. Cancer refers to the uncontrolled proliferation of cells. Invasive cancer cells invade adjacent tissue, facilitating cancer growth. Metastatic the ability of cancer cells to travel to different sites in the. Persistent uncontrollable cell proliferation in different areas of the body. body and invade to form new tumours. Immortal cancer cells do not die, they continually divide. nutrients. This is a critical step to allow them to proliferate. Angiogenesis cancer cells develop their own blood vessels to supply. Radiation high energy radiation is used to shrink tumours and kill cancer cells. Radiation therapy damages dna of both cancerous and non- cancerous cells. Chemotherapy drugs are used to treat cancer. As cancerous cells are dividing rapidly, chemotherapeutic drugs target rapidly dividing cells. As the treatment of cancer involves targeting cell proliferation, an understanding of the cell cycle is essential for understanding the mechanism of drug action. replicate.

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