Physiology 1021 Lecture Notes - Lecture 1: Uniporter, Collecting Duct System, Proximal Tubule

• School: Western University
• Department: Physiology
• Course: Physiology 1021
• Professor: John Ciriello

Document Summary

Renal physiology: regulation of extracellular fluid volume and bp, regulation of osmolarity, maintain ion balance, ph, excretion of wastes (creatine; urea) Collect urine blood cells) carbohydrates: gluconeogenesis (making glucose from non, production of hormones (epo stimulates red. Made of renal corpuscle (cid:523)glomerulus and bowman"s capsule(cid:524) and the tubule (cid:523)made of one layer of. Functional unit (roughly 1 million per kidney) epithelia cells: cortical nephrons. Juxtaglumerular apparatus: junction of late ascending loop of henle that passes between afferent and efferent arterioles. Glumerulus: fenestrated capillary; made of enfothelium cells. Everything but wbc and rbc can filter out. Barriers to filtration: size of pores in the capillaries (glomerulus, basal lamina, size of slits between podocytes. Heart artery arteriole capillary arteriole capillary . 20% of cardiac output goes to kidneys, and is filtered through the glomeruli. 20% of this plasma is filtered into lumen of the nephron. Kidney function is determined by how much blood is filtered into the nephrons per day.