Physiology 2130 Lecture Notes - Lecture 5: Endoplasmic Reticulum, Troponin T, Troponin C
Document Summary
Muscles = biological machines that utilize chemical energy from the breakdown and metabolism of food to perform useful work. 3 kinds of muscle cells: skeletal: used primarily for voluntary motion, smooth: found within the walls of blood vessels, airways, various ducts, urinary bladder, uterus and digestive tract, cardiac: found in the heart. Body contains over 600 different muscles: perform 3 different principal functions. Whole muscles are made up of bundles of fasciculi. Each fascicle is made up of groups of muscle cells or fibers: each fiber is an elongated cell with many nuclei. Each muscle cell contains many bundles of myofibrils. Each myofibril contains thin and thick myofilaments (made of protein: the regular arrangement of of these filaments gives skeletal muscles it"s stripped appearance. Thin myofilaments contain mostly the protein actin along with troponin and tropomyosin. The interaction of thin and thick myofilaments results in muscle contraction.