Physiology 2130 Lecture Notes - Lecture 13: Endocrine System, Body Fluid, Dwarfism

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Introduction: the endocrine system consists of a series of glands that secrete different chemicals into the blood, these hormones then travel throughout the body to their target site to initiate their effect. Hydrophilic therefore they can circulate freely in the blood. Hydrophilic therefore they can"t diffuse through the cell membrane. Receptor must be located on the cell membrane of the target cell since it can"t diffuse into the cell. Hydrophobic therefore they require a protein carrier to help them circulate in the blood. Hydrophobic therefore they can diffuse easily through the cell membrane. Receptor-located inside the target cell: notice that whether the hormone is hydrophilic or hydrophobic determines how it is carried and acts on the target cell. Control of secretion: secretion of most hormones is controlled by negative feedback, set point control center effector controlled variable sensor, back to control center. It is also involved in regulating the behavioural drives of thirst, hunger, and sexual behaviour.

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