Physiology 3120 Lecture Notes - Lecture 4: Duodenum, Solution, Lymphatic System
28 Dec 2017
School
Department
Course
Professor
Document Summary
Fluid shifts at the cell membrane movement between icf and ecf. Helps determine the net movement of water across the cell membrane (between icf and. A way to look at relative changes in the volume and concentration of the icf and ecf compartments. 2 compartments: icf is 28l and ecf is 14l. Everything occurs relative to the 0 point. Initial changes always occur to the ecf compartment first. Pure water is hypotonic (lower concentration than body fluids) Water load (drinking water): affects the ecf first. Initial: volume of ecf increases and osmolality (concentration) decreases, ecf becomes diluted. Pure water distributes itself in the same ratio as the volumes of the two compartments. Final: volume of both compartments increases, osmolality of both compartments will decrease compared to the normal osmolality of 300 mosm/kg. Sweating losing water in ecf first (it is the fluid that is in contact with external environment) Initial: ecf volume decreases and osmolality increases.
