Physiology 3140A Lecture Notes - Lecture 7: Phospholipid Scramblase, Flippase, Homeosis
28 Dec 2017
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Document Summary
Membranes contain lipid, protein and also glycolipids and glycoproteins. Compositions vary between different organelles and within the membrane itself: some regions have more cholesterol/lipids than others. Recycling exists between membranes (grows by inserting individual components like proteins and lipids in to get larger) 0: liver/erthyrocytes: half lipid, half protein and little carbohydrates. Specialized membranes: myelin: mostly lipid and low protein and carbohydrates, mitochondrial inner membrane: mostly protein, low lipid and no carbohydrates. The lipid bilayer is asymmetric: what is inside of the cell is different than the outside. Inner and outer leaflets have different lipids types and compositions. Asymmetry provides curvatures of membranes: directs overall shape of cell or organelle, level of saturation of the phospholipids allow for more/less curvature of the plasma membrane. Directs the overall shape of the membrane or organelle. If there are many unsaturated fatty acids on the outside of the membrane and many saturated fatty acids on the inside of the membrane, it provides curvature.
