Psychology 2220A/B Lecture Notes - Lecture 15: Nigrostriatal Pathway, Midbrain, Cerebrum

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Once swallowed the drugs dissolve in the fluids of the stomach and are carried to the intestine where they are absorbed into the bloodstream. Drugs that are not readily absorbed from the digestive tract or that are broken down into inactive metabolites before they can be absorbed must be taken by some other route. Some drugs act diffusely on neural membranes throughout the cns. Others act in a more specific way: by binding to particular synaptic receptors. Conditioned compensatory response are conditional stimuli that predict drug administration come to elicit conditional responses opposite to the unconditional effects of the drug. Cocaine addicts tend to go an cocaine sprees which are binges of extremely high levels of intake maintain for a few days, during the sprees the users become increasingly tolerant to the euphoria producing effects of cocaine. The sprees end when the cocaine is gone and the user suffers from cocaine psychosis.

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