Rehabilitation Sciences 3360A/B Lecture Notes - Lecture 2: Epiphyseal Plate, Tendon Cell, Synovial Sheath
21 Apr 2016
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Document Summary
Tissue; aggregate of cells that have similar structure & function: connective, epithelial, muscle, nervous. Classes of connective tissue: blood, bone, cartilage, connective tissue proper, dense, loose. Fibers (collagen ad elastin: cellular component (resident cells) The gross anatomic structure & microarchitecture of connective tissue varies. The function of connective tissue is primarily determined by the ecm components. Ground substance also called interfibrillar component of ecm organic gel that contains water to reduce friction between fibers, transports nutrients and metabolites and maintains space between fibres primarily proteoglycans & hyaluronic acid. Consists of glycosaminoglycan (gag) chains attached to a core protein. Function to: hydrate the ecm, stabilize collagen networks, resist compressive forces. Type and amount of proteoglycans in a tissue is proportional to the types of compressive & tensile forces the tissue undergoes. Provides functional integrity of connective tissue structures: arrangement of collagen fibers varies, progressive winding of fibers to increase strength of collagen.
