PS280 Lecture Notes - Lecture 6: Major Depressive Disorder, Major Depressive Episode, Hypomania

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13 Jun 2018
School
Department
Course
Mood Disorders
Depressive Disorders
Major depressive disorder
Persistent depressive disorder (dysthymia)
Bipolar Disorders
Bipolar I and II disorders
Cyclothymic disorder
____________________________________________________________________________
Depression
Major Depressive Disorder
Clinical description - symptoms
Depressed mood
Anhedonia → losing interest or pleasure in things you usually enjoy
One of these two symptoms required but most often present together
Difficulty concentrating and/or difficulty making decisions → eg deciding what to
eat/wear, decisions that used to be simple
Difficulty sleeping → sleeping too much or not being able to sleep, early morning
awakening
Increased or decreased weight/appetite → people often lose weight when they
are not trying to lose weight, not going to same effort to eat or make meals
Psychomotor agitation or retardation → either moving more slowly or unable to sit
still, is it noticeable to other people?
Decreased energy → even if people sleeping more
Worthlessness and/or guilt → guilt can be about things they have done or not
done, things from the past, guilt around not enjoying activities for eg
Suicide ideation
Symptoms present most of the day, nearly every day for 2 weeks
Must have one of the first two and at least 5 of the other 9 symptoms
Single episode or recurrent
No manic/hypomanic episodes
50% of people who recover from an episode of depression have a 2nd episode
Average = 4 episodes
Persistent Depressive Disorder
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Clinical description - similar to major depression but different course
Persistently depressed mood for 2+ years
Cannot be symptom free > 2 months
Milder symptoms
Low mood more days than not
2 more symptoms on top of low mood → for eg low self esteem and
difficult decision making
Depressive Disorders
Overlap → suffer from both: persistent and major
Bipolar Disorders
Mania (1 week) and hypomania (4 days)
Elevated mood → high, excited, hyper, elated, must be present for diagnosis of mania or
hypomania
Grandiosity → inflated self esteem, may believe oneself has special
talents/powers/abilities
Less need for sleep
Increased activity → work, socially
Reckless activity → for eg investing money
Rapid speech → unusually talkative without regard for others
Flight of ideas → so many ideas in their heads they can’t get them all out, might cause
others to feel overwhelmed
Distractibility
Bipolar I
Manic episode(s)
(Major depressive episodes) → is not required but vast majority of people diagnosed
have both
Bipolar II
Major depressive episode(s)
Hypomanic episode(s)
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Document Summary

Anhedonia losing interest or pleasure in things you usually enjoy. One of these two symptoms required but most often present together. Difficulty concentrating and/or difficulty making decisions eg deciding what to eat/wear, decisions that used to be simple. Difficulty sleeping sleeping too much or not being able to sleep, early morning awakening. Increased or decreased weight/appetite people often lose weight when they are not trying to lose weight, not going to same effort to eat or make meals. Decreased energy even if people sleeping more. Worthlessness and/or guilt guilt can be about things they have done or not done, things from the past, guilt around not enjoying activities for eg suicide ideation. Symptoms present most of the day, nearly every day for 2 weeks. Must have one of the first two and at least 5 of the other 9 symptoms. 50% of people who recover from an episode of depression have a 2nd episode.

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