ADMS 3502 Lecture 18: Acute and Chronic Renal Failure
21 May 2020
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Document Summary
Renal disease is one of the leading diseases of morbidity. All organ systems are affected by renal insufficiency. A sudden reduction in kidney function, leading to the retention of products normally excreted by the kidney. Types: pre-renal problems in perfusion to the kidney, like decreased cardiac output, renal intrisic problem of the renal tissue. Glomerular, tubular: post-renal obstruction, for example, at the collecting duct leading to retention. Na+, retention of na+: elevated urea out of proportion to creatinine *this is a distinguishing characteristic of pre-renal failure. Urea = 8. 0mmol/l (n:3-8mmol/l), creatinine = 110 mol/l (n:60-120 mol/l) 3 days later: afebrile, but feeling badly, bp = 110/60, dizzy when standing up, decreased jugular venous pressure, mucous membranes dry, urea = 27mmol/l, creatinine = 290 mol/l. Interpretation of case 1: upon admission, it would have been best to avoid aggressive diuretic therapy. The diuretic, which she did not need (indication of.
