KINE 2011 Lecture Notes - Lecture 14: Osmosis, Hydrophile, Lipid Bilayer

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Facilitated: diffusion w/aid: diffusion of polar & charged molecules (water, amino acids, facilitated diffusion depends on concentration gradient. 2 groups of facilitated diffusion: channel & carrier. Channel: form hydrophilic pathways in membrane through which molecules can, channels aid in diffusion of molecules by providing path that is shielded by hydrophobic core, ex: aquaporinis facilitate diffusion of water. Gated channel: transported that switch b/t open, closed & intermediate states, gates open/closed by olvoltage changes across membrane, ope(cid:374)i(cid:374)g/closi(cid:374)g cha(cid:374)ges i(cid:374) protei(cid:374)"s 3d co(cid:374)for(cid:373)atio(cid:374) Carrier: form passageways through lipid bilayer, each carrier protein binds a single molecule & moves it across, protein undergoes conformation changed. Osmosis- passive diffusion of water: osmosis: diffusion of water through a selectively permeable membrane. Osmosis through simple diffusion of facilitative by aquaporin: movement of water causes cell to shrink & swell, hypertonic: if solutes in surrounding solution are at lower, hypotonic: solutes in surround solution are at higher concentration than cell.

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