KINE 2011 Lecture Notes - Lecture 17: Phospholipid, Fluid Mosaic Model, Lipid Bilayer

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Structure of membrane: plasma membrane: are selectively permeable membrane barrier, allows for uptake of nutrients, elimination of waste, protect internal cell from environment, provides support & protection, internal membrane result in compartmentalization & complexity. Membrane: fluid mosaic model: phospholipid bilayer w/embedded proteins, cholesterol, lipids & proteins have carbohydrate links forming glycoproteins & glycolipids, external membrane: more glycolipids & carbohydrates, internal membrane: cytoskeleton bonded to proteins. Bilayer: double layer of lipid molecules: head: consists of glycerol, alcohol/amino & phosphate group, Polar, hydrophilic: fatty acid tails: hydrocarbon chain, non-polar, hydrophobic, considered amphipathic- both hydrophobic. & hydrophilic: fatty acids differ in degree of saturation- thus effecting fluidity of membrane. 3 formations of phospholipids: micelles, liposome or bilayer: formation is based on external environment, hydrophobic effect: tendency of non- polar tails to reside in center, w/hydrophilic tails on outside to interact w/water. Fatty acids control movement of polar substances through membrane: detergent is attracted to both oil & water.

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