KINE 2011 Lecture Notes - Lecture 18: Sister Chromatids, Centromere, Dna Replication

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Genetic material (heritable information: dna located in nucleus, organized into chromosomes, chromosomes are part of chromatin. Euchromatin & heterochromatin: euchromatin: loosely packed regions, genes active in rna transcription, heterochromatin: densely packed masses, genes are inactive, fold & packs to form thick, rod like chromosomes during nuclear division. Chromosomes & cell division: daughter cells are identical copies of parent cell, this means each daughter cell contains exact same heritable material (dna) as parent cell did, dna must be replicated, dna in each chromosome must be replicated. Chromosomes & cell division: number of different chromosomes, does not change following replication- only amount of dna changes, before replicatio(cid:374) there are x a(cid:373)ou(cid:374)t of dna, after replicatio(cid:374) there"s 2x. Dna replication & chromatids: after dna replicates, it condenses (folds & coils), giving it a short cubby appearance, in this form, each dna replication is chromatid, chromatid always occurs in pairs called sister chromatids.

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