HUBS192 Lecture Notes - Lecture 49: Inner Cell Mass, Primitive Streak, Zona Pellucida

• School: University of Otago
• Department: Human Body Systems
• Course: HUBS192
• Professor: Greg Jones

Document Summary

Synctiotrophoblast layer secretes special enzymes, break down and invade the endometrial layer. Note: monozygotic twins: 2 umbilical cords to 1 placenta! Need research into development biology; understand normal developmental processes and how they re affected by the environment or chemical compounds, a lot of chemicals that can cross the placenta into foetus. Pathways for development are also reactivated by cancer. At morula stage : a ball of cells. Initially, cells are totipotent can develop into any cell in your body (also including placenta) Blastocysts: 2 types of cells: trophoblast restricted cell fate: placenta. Inner cell mass: form embryo, amniotic membrane as well (there s now a restriction of cell fate) Cells of inner cell mass are pluripotent, can form almost any cell type (except what the trophoblast does: villi of placenta) These are the cells that embryonic stem cells derived from. Esc are derived from inner cell mass (pluripotent, and can form all cell tissues of the adult)