ESPM 165 Lecture Notes - Ester, Carnitine, Myocyte

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More reduced, more combustion and more e- transport. The body has 100x more energy in lipids than sugars. Free fatty acid: carboxylic acid with acyl chain, free is not chemically linked to anything else. Triacylglycerol: three fatty acids esterified on to a glycerol head group. Carrier is coenzyme a, long flexible arm with thiol at the end capable of acting as an ester. Digested fatty acids are absorbed in the small intestine: myocytes and adipocytes are major consumers, targets, other mechanisms to get secretions of emulsifiers too. Lipids are transported in the blood as chylomicrons: proteins, apolipoproteins, coating them. Mobilization is a bit different directed by hormones: stored in lipid droplets, low carbon, low energy, mediated by glucagon, phosphorylate perilipins: surface coat proteins that direct mobilization. In the blood stream, bound by serum albumin: small protein carrier of fatty acids in blood. B oxidation is coupled to citric acid cycle, happening inside mitochondria.

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