MCELLBI 32 Lecture Notes - Lecture 5: Pulmonary Edema, Lipid Bilayer, Facilitated Diffusion

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Membrane transport regulates what gets into internal environment. Disaccharide is least likely to diffuse through the phospholipid bilayer of the plasma membrane. Polar molecules get through membrane with help of transporter proteins, ion channels-->facilitated diffusion. Molecules will move from high to low concentration. Key points: molecules are moving randomly, molecules go both directions, net movement from high to low c. Factors affecting diffusion rate: concentration gradient, surface area of membrane, membrane permeability of molecule, molecule size. 5. diffusion distance diffusion rate is proportional to delta c*sa*p/distance. Pulmonary edema fluid buildup in the interstitial lung space. When glucose binds, the transporter changes shape and brings glucose to other side. ->rate of facilitated diffusion flattens out after a certain point since transporters get saturated. ->increase rate of facilitated diffusion by making more transporters. ->channels that allow ions across, can be very specific, some channels open and close, thus allowing regulation of ion flow. ->some have gates that can open and close.

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