ANTH 337 Lecture Notes - Lecture 6: Restriction Fragment Length Polymorphism, Dna Profiling, Sanger Sequencing
Document Summary
Genetics: heredity; passage of genes between generations: meiotic drive: competition in haploid cells to become diploid, development: zygote to organism. 2 roles of dna: transmit information between generations. During meiosis: recombination of genes from mother and father to go n to 2n: build/maintain organism. Hox: conserved genes in producing proteins; important for building body plans. Basal metabolic rate: the energy to maintain body when doing nothing. Allostatic load: keeping body at normal range, the amount of stress affects it, more stress= higher allostatic load. Rflp: enzymes cut at certain parts in sequence where know mutations existed, first method of dna profiling. Dna sanger sequencing: actually synthesizing pieces of dna, determining order of nucleotide sequences. Snp chips: screening genome for known polymorphisms, problem: what population did they come from. Strs: microsatellites, repeat regions of the genome, found throughout the genome. Only 1 copy per person, only passed through mother.
