BIOLOGY 173 Lecture 15: Anatomy 10/5/2016

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Spongy or cancellous bone structure porous: trabecular pieces of bony plats form 3d lattice, haversian canal (lengthwise/ vertical, volkman"s canal or perforating canal (horizontally) Matrix (extracellular) 98: inorganic 65% Two types: intramembranous (dermal) ossification bones develop from fibrous ct membrane, ex. Ossification center is formed in a fibrous membrane mesenchymal (stem) cells cluster in the fibrous membrane and differentiate into. Osteoblasts secrete collagen (the organic matrix) which them calcifies. Spongy bone if formed small pieces of hard matrix form trabeculae. On the outside mesenchymal cells form the periosteum. Compact bone is formed on the outer surfaces deep to the periosteum. Compact bone is formed when the spongy bone in this region is more heavily calcified and the structure is remodeled to form osteons: endochondral ossification, ex. Fibroblasts migrating with the blood vessels differentiate into osteoblasts and form primary ossification center in diaphysis. Remaining cartilage: articular cartilage (hyaline, epiphyseal plate (growth plate)

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