BIOLOGY 242 Lecture Notes - Lecture 32: Glycogen, Menopause, Small Intestine

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Effects on the host: germ free animals: louis pasteur. Underdeveloped immune system, lack antibodies to normal flora, vulnerable to opportunistic pathogens. Require vitamins k and more b vitamins. Normal flora provide defense against pathogen competition for nutrients, production of inhibitory compounds. Treating skin with hexachlorophone gram + replaced with gram -, leads gram infections. Characteristics (of normal flora: adherence- to host surfaces/cells. Specific receptors, s. salivariase (tongue), s. mutans (tooth), glycocalyx fimbriae: antimicrobial substances. Stomach: numbers low (10/ml, mostly transient, hydrochloric acid, digestive enzyme, lactobacillus, candida. Small intestine: duodenum, jejunum, numbers low (103/ml) Large intestine (colon: numbers very high, 25% of feces, 1011/gram, 300+ species, mechanical movement, desquamation, mucus, anaerobic bacteria predominant. Genitourinary tract: upper- free of mos, lower urethra- numbers fairly low. Flushing by urine, antibacterial mucous: adult female genital tract. Estrogen stimulates the accumulation of glycogen in vaginal walls.

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