BIOLOGY 445 Lecture Notes - Lecture 11: Constipation, Pramlintide, Cholinergic
Document Summary
11a: anesthetics- general & local: describe the types of anesthesia, general. Inhaled: balanced, regional, spinal, epidural, local, topical. Infiltration: nerve block, list the effects and stages of general anesthesia, effects , analgesia: the inability to feel pain, amnesia: a partial or total loss of memory, loss of consciousness. Induction stage 1 to 3: propofol, etomidate, ketamine (iv medications, maintenance at stage 3. Addiction: drug interactions alcohol or can depressants-hypotension, coma or respiratory depression. P450 metabolism increased and prolonged sedation when taken in combination with cimetidine, ketoconazole, fluvoxamine, fluoxetine, and omeprazole. Slows elimination of phenytoin: morphine, therapeutic overview, etiology of pain, synaptic transmission. G-protein coupled receptors: nomenclature and classification, morphine (schedule 2 drug), moderate to severe pain, sedation, Natural opiate: pharmacokinetic characteristics, readily absorbed from gi tract. Conjugation with glucuronic acid in liver, excreted in urine: pharmacodynamic characteristics, opioid receptor agonist ( >> = ).