CAS PS 231 Lecture Notes - Lecture 7: Grey Matter, Frontal Lobe, Temporal Lobe
12 Mar 2018
School
Department
Course
Professor
Document Summary
The neuroanatomy of schizophrenia: some schizophrenics show mild abnormalities of brain anatomy that varies, on average. Less than average gray matter and white matter. Thalamus also smaller than average for schizophrenics. In the study in 15. 14, strongest deficits were in the left temporal and frontal areas of the cortex. Cell bodies smaller than normal, especially in hippocampus & pfc. Lower than normal activity in left hemisphere. Inconsistent results as to whether the brain damage associated with schizophrenia is progressive; most of the damage though is apparently early, later changes are relatively small. These results suggest a subtle change in brain development; reasons behind the brain abnormalities are not certain; many schizophrenics use alcohol, drugs, etc. some of the brain abnormalities may result from heavy drug use. Research method for understanding neuroanatomy of schizophrenia: monozygotic twins discordant for schizophrenia one has schizophrenia, the other doesn"t.
