SAR HS 300 Lecture 4: Screening for disease part 3

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Among those tested, ___ % of the people with *disease* screened positive by the ___ test. If a person has *disease* there is a ___% probability that the ___ test will be positive. Among those tested, ___ % of the people without *disease* screened negative by the ___ test. If a person does not have *disease* there is a ___% probability that the ___ test will be negative. To improve sensitivity: cut off is moved farther in the range of the non-diseased (towards a) To improve specificity: cut off should be moved farther in the range typically associated with the disease (towards c) False positive and false negative areas on the graph. Successful screening will balance the cut off point criteria so that both over referrals and under referrals for diagnostic tests are minimized. Effect of prevalence of a disease on the screening test results. Stable properties of screening tests: unaffected by prevalence of disease.

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