BIOL-2230 Lecture Notes - Lecture 17: Asthma, Exhalation, Functional Residual Capacity

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In nose: allow us to smell, external nares, entry holes to nasal cavity, vestibule, more space after external nare, lined with vibrissae (hairs) Internal nares: constricted area at back of nasal cavity, slows air movement, chance to warm and humidify it, paranasal sinuses, hollow cavities in facial bones, lighten skull and function in nasal quality. Important for keeping lungs attached to chest cavity while it changes shape as we breathe: pulmonary ventilation. Intrapleural pressure: pressure in pleural cavity (outside lungs, transpulmonary pressure, difference between intrapleural pressure and intrapulmonary pressure, lungs stay inflated because pressure inside them is always greater than the pressure outside them, bo(cid:455)le"s la(cid:449) Intrapleural is negative compared to intrapulmonary: relationship between pressure and volume, p1v1=p2v2, volume and pressure are inversely related, one increases, the other decreases. Internal respiration oxygen: capillary po2 = 104 mmhg, tissue po2 = 40 mmhg, oxygen diffuses out of blood until equilibrium of 40 mmhg is reached, near perfect transfer.

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