FGSS 2140 Lecture Notes - Lecture 22: Transitional Fossil, Sertoli Cell, Dehydroepiandrosterone

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Lecture 22: treatments for infertility, surgery: (1) fibroid tumors and endometriosis, (2) tubal blockage: microsurgery to repair oviduct, though scar tissue may form, artificial insemination, oligospermic: aih. C. if husband is azoospermic, use donor (aid) Mullerian inhibiting substance in text) this allows the leydig cells to differentiate, make testosterone/dht, and develop the male duct system. A. lacks both testosterone and amh, so mullerian duct is allowed to develop and. Wolffian duct regresses: brain differentiation during fetal life, non-primates: programmed for cyclic or tonic gonadotropin release, cyclic release: female. A. increase in gnrh which gives way to extreme rise in fsh/lh that begins 1-2 years in females before males. Lh levels rise in amplitude of hour-to-hour changes in secretion (in adults, levels fluctuate less). For males, this allows for onset of spermatogenesis and rise in t: estrogens rise in pubescent females (due to growing follicles in ovary), causing breast maturation. They continue to rise as female approaches menarche.

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