BIOSC-116 Lecture Notes - Lecture 22: Axon Hillock, Threshold Potential, Cell Membrane

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The threshold level of depolarization has been reached at the axon hillock. Na+ voltage gated channels to open causing a rapid depolarization of the axon. These channels open when the membrane potential hits -55 mv (threshold potential). Gates of sodium channels open and sodium will flow in very quickly, as it flows in, the inside of the membrane starts to become positive (+30) At -55 voltage gated channels open which allow sodium to flow into the axon from both sides and it will depolarize the axon to the point where the axon potential reverses it becomes positive (+30) As na+ ions flow into the axon, their positive charges start to reduce the negative charge within. Na+ ions diffuse along the inside of the membrane, once the threshold level of depolarization is reached it will trigger the next voltage gated na+ channels to open etc. Once the threshold level of depolarization has been reached the action potential starts and is self-propagating.

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